Promethease 0.1.82

From SNPedia

Stroke, also known clinically as a cerebrovascular accident, is defined as a disturbance in the flow of blood to the brain and the consequent loss of brain function. It is one of the leading causes of death worldwide; more information is available at Wikipedia.

SNPs affecting the risk of one or more types of stroke include the following:

• rs1401296, in the PROC gene
• rs6025, known as F5 Leiden
• rs3030341
• rs6797312, in the SERPIN1 gene
• rs5443, in the GNB3 gene
• rs173686, in the CSPG2 gene, linked to intracranial aneurysm

One or more SNPs in the following genes have also been linked to stroke risk:

• PDE4D
• APOE

In Asian patients, two SNPs in the PRKCH gene have been linked to cerebral infartions:

• rs2230500, also known as 1425G/A
• rs3783799, also known as SNP_15