Rs6797312
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs6797312 |
| hapmap | rs6797312 |
| hgdp | rs6797312 |
| ensembl | rs6797312 |
| gopubmed | rs6797312 |
| scholar | rs6797312 |
| rs6797312 | |
| pharmgkb | rs6797312 |
| hgvbaseg2p | rs6797312 |
| medrefsnp | rs6797312 |
| 23andMe | rs6797312 |
| SNP Nexus |
| Gene | SERPINI1 |
| Chromosome | 3 |
| Orientation | plus |
| Position | 168969996 |
| Genotype | Effect |
|---|---|
| rs6797312(A;A) | 2x higher stroke risk in Caucasian women |
| rs6797312(A;T) | 2x higher stroke risk in Caucasian women |
| rs6797312(T;T) | normal |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs6797312(A;A) | 2x higher stroke risk in Caucasian women | |
| Rs6797312(A;T) | 2x higher stroke risk in Caucasian women | |
| Rs6797312(T;T) | normal |
rs6797312, a SNP in the neuroserpin SERPINI1 gene, was found to be associated with stroke risk in some populations but not others.
In a study of 224 female patients (from 15-49 years old) equally divided between Caucasians and African-Americans, the rs6797312(A) allele was associated with higher risk (odds ratio 2.05, p=0.023) for early-onset ischemic stroke in Caucasians but showed no association in African-Americans.[PMID 17961231]
