Rs3783799

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is asnp
is mentioned by
dbSNPrs3783799
hapmaprs3783799
hgdprs3783799
ensemblrs3783799
gopubmedrs3783799
scholarrs3783799
googlers3783799
pharmgkbrs3783799
hgvbaseg2prs3783799
medrefsnprs3783799
23andMers3783799
SNP Nexus

GenePRKCH
Chromosome14
Orientationminus
Position60988968
GenotypeEffect
rs3783799(A;A)1.4x increased risk for stroke
rs3783799(A;G)1.4x increased risk for stroke
rs3783799(G;G)normal risk


Genotypes Magnitude Summary
Rs3783799(A;A) 1.4x increased risk for stroke
Rs3783799(A;G) 1.4x increased risk for stroke
Rs3783799(G;G) normal risk
A common SNP only in Asian populations, this SNP and a close neighbor also in PRKCH gene, rs3783799, have been associated with higher risk for subcortical silent brain infarction, a common form of stroke.

The odds ratio for carriers of a risk allele is 1.27 (CI: 1.09-1.48, p=0.0026) compared to individuals homozygous for the non-risk allele, based on studies of ~300 Japanese patients. [PMID 18164711]

? (A;A) (A;G) (G;G)
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