From SNPedia
rs17696736 has been reported in a large study to be associated with type-1 diabetes.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.34 (CI 1.16-1.53), and for homozygotes, 1.94 (CI 1.65-2.29). [PMID 17554300]
In an expanded follow-up study of >6,000 controls and 6,000 patients, the heterozygote odds ratio for this SNP was recalculated to be 1.22 (CI 1.15–1.28). [PMID 17554260]
| ? | (A;A) (A;G) (G;G) |
|---|
 |
| GWAS
|
| SNP
| rs17696736
|
| PubMedID
| [PMID 17554260]
|
| Condition
| Type 1 diabetes
|
| Gene
| C12orf30
|
| Risk Allele
| G
|
| pValue
| 2.00E-016
|
| OR
| 1.22
|
| 95% CI
| 1.15-1.28
|
| GWAS snp
|
| PMID
| [PMID 18978792]
|
| Trait
| Type 1 diabetes
|
| Title
| Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
|
| Risk Allele
| G
|
| P-val
| 6E-18
|
| Odds Ratio
| NR NR
|
[PMID 19565500] Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis
Related to DIABETES MELLITUS, INSULIN-DEPENDENT, 20; IDDM20
according to
omim 612520. See
also
Related to DIABETES MELLITUS, INSULIN-DEPENDENT; IDDM
according to
omim 222100. See
also
