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rs17696736 has been reported in a large study to be associated with type-1 diabetes.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.34 (CI 1.16-1.53), and for homozygotes, 1.94 (CI 1.65-2.29). [PMID 17554300]
In an expanded follow-up study of >6,000 controls and 6,000 patients, the heterozygote odds ratio for this SNP was recalculated to be 1.22 (CI 1.15â€“1.28). [PMID 17554260]
|Condition||Type 1 diabetes|
|Trait||Type 1 diabetes|
|Title||Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci|
|Odds Ratio||NR NR|
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[PMID 19956108] Analysis of 55 autoimmune disease and type II diabetes loci: further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type I diabetes loci, and support for a new locus, 12q13.3-q14.1.
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|qualified_impact||Insufficiently evaluated pathogenic|
[PMID 23297363] Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot.
|Title||Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.|
|Odds Ratio||1.10 [1.06-1.14]|