From SNPedia
cancer-genetics these snps influence genetic risk for prostate cancer
[PMID 19366831] Genotyping 13 SNPs (including this one) in 1,308 Caucasian prostate cancer patients led to the conclusion that while none of the SNP associations were as significant as having a first-degree family history of the disease, they did replicate. And in fact, for rs2735839, the risk estimate varied by family history.
| ? | (A;A) (A;G) (G;G) |
|---|
 |
[PMID 19336566] Replication of the 10q11 and Xp11 Prostate Cancer Risk Variants: Results from a Utah Pedigree-Based Study.
Related to PROSTATE CANCER, HEREDITARY, 15; HPC15
according to
omim 611959. See
also
[PMID 19902474] Replication of prostate cancer risk loci on 8q24, 11q13, 17q12, 19q33, and Xp11 in African Americans
| PharmGKB | PA162356746 |
| Name | |
| Annotation | GWAS Results: Multiple newly identified loci associated with prostate cancer susceptibility (Initial Sample Size: 1,854 cases, 1,894 controls; Replication Sample Size: 3,268 cases, 3,366 controls; Risk Allele: rs2735839-G). |
| Gene | KLK3 |
| Featue | |
| Evidence | PubMed ID:18264097; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Prostatic Neoplasms |
| Curation Level | Non-Curated |
