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rs2735839(A;A)

From SNPedia
in prostrate cancer patients, this is statistically associated with a somewhat more aggressive cancer
Is agenotype
ofrs2735839
GeneKLK3
Chromosome19
Position50,861,367
mentionedby
Magnitude1.8
ReputeBad
Geno Mag Summary
(A;A) 1.8 in prostrate cancer patients, this is statistically associated with a somewhat more aggressive cancer
(A;G) 1.6 in prostrate cancer patients, this is statistically associated with a somewhat more aggressive cancer
(G;G) 0

Based on a He et al. 2014 Clin Can Res article, the rs2735839(A) allele is associated with more aggressive prostate cancer in general, and Gleason score 7 patients, with increased risk of being GS 4 + 3 compared to GS 3 + 4 (odds ratio 1.85, CI: 1.31–2.61).