From SNPedia
| Geno
|
Mag
|
Summary
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| (A;A)
|
|
1.3x higher risk for spondylitis
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| (A;G)
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1.3x higher risk for spondylitis
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| (G;G)
|
0
|
normal risk
|
| ? | (A;A) (A;G) (G;G) | 28 |
|---|
 |
is one of several SNPs in the
IL23R gene that has been shown in a large (over 1,000 Caucasian patients) study to be associated with
ankylosing spondylitis. The odds ratio is 1.3 (p=7.5x10e-9).[
PMID 17952073,
PMID 18037607]
[PMID 18713787] rs11209032 and rs1495965 no significant association with systemic sclerosis
[PMID 19034457] Lack of association between interleukin 23 receptor gene polymorphisms and rheumatoid arthritis susceptibility
[PMID 20375120] IL-23R gene confers susceptibility to Behcet's disease in a Chinese Han population
[PMID 19690863] Single-nucleotide polymorphisms and expression of IL23R in Chinese ankylosing spondylitis patients
[PMID 22089529] Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis
