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rs11614913

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 2 Somewhat increased risk of various types of cancer
(C;T) 0 normal
(T;T) 2 decreased risk for colorectal cancer and lung cancer
ReferenceGRCh38 38.1/141
Chromosome12
Position53991815
GeneMIR196A2
is asnp
is mentioned by
dbSNPrs11614913
dbSNP (classic)rs11614913
ClinGenrs11614913
ebirs11614913
HLIrs11614913
Exacrs11614913
Gnomadrs11614913
Varsomers11614913
LitVarrs11614913
Maprs11614913
PheGenIrs11614913
Biobankrs11614913
1000 genomesrs11614913
hgdprs11614913
ensemblrs11614913
geneviewrs11614913
scholarrs11614913
googlers11614913
pharmgkbrs11614913
gwascentralrs11614913
openSNPrs11614913
23andMers11614913
SNPshotrs11614913
SNPdbers11614913
MSV3drs11614913
GWAS Ctlgrs11614913
GMAF0.388
Max Magnitude2
? (C;C) (C;T) (T;T) 28


[PMID 18521189OA-icon.png] miRNA sequences and non-small cell lung cancer


[PMID 25557604] The association of common polymorphisms in miR-196a2 with waist to hip ratio and miR-1908 with serum lipid and glucose

rs11614913 SNP in hsa-mir-196a2 was associated with survival in individuals with NSCLC. Specifically, survival was significantly decreased in individuals who were homozygous CC at SNP rs11614913.

[PMID 18634034] microRNA 1,009 breast cancer cases and 1,093 controls in a population of Chinese women

snp near microRNA
ACC MI0000279
ID hsa-mir-196a-2
offset -22


[PMID 19293314] A Functional Genetic Variant in microRNA-196a2 Is Associated with Increased Susceptibility of Lung Cancer in Chinese.


[PMID 19514064] Functional variant in microRNA-196a2 contributes to the susceptibility of congenital heart disease in a Chinese population


[PMID 19567675OA-icon.png] microRNA miR-196a-2 and Breast Cancer: A Genetic and Epigenetic Association Study and Functional Analysis

[PMID 19834808] Association of MicroRNA-196a-2 Gene Polymorphism with Gastric Cancer Risk in a Chinese Population

[PMID 19847796] Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases


[PMID 20188135] Association of a variant in MIR196A2 with susceptibility to hepatocellular carcinoma in male Chinese patients with chronic hepatitis B virus infection


[PMID 20229273] A polymorphism of microRNA196a genome region was associated with decreased risk of glioma in Chinese population

[PMID 20488170] Common genetic polymorphisms in pre-microRNAs were associated with increased risk of dilated cardiomyopathy

[PMID 20501619OA-icon.png] Mature miRNA sequence polymorphism in MIR196A2 is associated with risk and prognosis of head and neck cancer

[PMID 20549817OA-icon.png] Genetic variants in selected pre-microRNA genes and the risk of squamous cell carcinoma of the head and neck

[PMID 20640596] The association between two polymorphisms in pre-miRNAs and breast cancer risk: a meta-analysis

[PMID 20722507] A functional variation in pre-microRNA-196a is associated with susceptibility of esophageal squamous cell carcinoma risk in Chinese Han

[PMID 20842445] Genetic variation in microRNA genes and prostate cancer risk in North Indian population

[PMID 20848167] Association Study of Common Genetic Variants in Pre-microRNAs in Patients with Ulcerative Colitis

[PMID 21073609] Association Between Common Genetic Variants in Pre-microRNAs and Gastric Cancer Risk in Japanese Population

[PMID 21080878] A variant in microRNA-196a2 is associated with susceptibility to hepatocellular carcinoma in Chinese patients with cirrhosis

[PMID 21241442] A variant in microRNA-196a2 is not associated with susceptibility to and progression of colorectal cancer in Chinese


[PMID 21565628] A Functional Variant in MicroRNA-196a2 Is Associated with Susceptibility of Colorectal Cancer in a Chinese Population


[PMID 21962133] Single Nucleotide Polymorphism in hsa-mir-196a-2 and Breast Cancer Risk: A Case Control Study


[PMID 21565178] Association between SNPs in pre-miRNA and risk of chronic obstructive pulmonary disease


[PMID 22291993OA-icon.png] A Genetic Variant in miR-196a2 Increased Digestive System Cancer Risks: A Meta-Analysis of 15 Case-Control Studies


[PMID 22659075] Association of the miR-146aC>G, miR-196a2C>T, and miR-499A>G polymorphisms with moyamoya disease in the Korean population

[PMID 19047128OA-icon.png] Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.

[PMID 19138993OA-icon.png] Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk.

[PMID 19232555OA-icon.png] Signatures of purifying and local positive selection in human miRNAs.

[PMID 19423719OA-icon.png] Update in lung cancer 2008.

[PMID 19458495OA-icon.png] Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes.

[PMID 19617315OA-icon.png] SNPs in human miRNA genes affect biogenesis and function.

[PMID 19881472] Common genetic variants in pre-microRNAs are associated with risk of coal workers' pneumoconiosis.

[PMID 20428464OA-icon.png] MicroRNA polymorphisms: a giant leap towards personalized medicine.

[PMID 20520619] Common genetic variants in pre-microRNAs and risk of gallbladder cancer in North Indian population.

[PMID 21319225] Common genetic polymorphisms in pre-microRNAs and risk of cervical squamous cell carcinoma.

[PMID 21345130] Investigative role of pre-microRNAs in bladder cancer patients: a case-control study in North India.

[PMID 21625865] A genetic variant in microRNA-196a2 is associated with increased cancer risk: a meta-analysis.

[PMID 21663520] Association between single-nucleotide polymorphisms in pre-miRNAs and the risk of asthma in a Chinese population.

[PMID 21692953] A functional polymorphism in pre-microRNA-196a-2 contributes to the susceptibility of hepatocellular carcinoma in a Turkish population: a case-control study.

[PMID 21902575] Genetic variants in miR-146a, miR-149, miR-196a2, miR-499 and their influence on relative expression in lung cancers.

[PMID 22074121] Associations of miRNA polymorphisms and female physiological characteristics with breast cancer risk in Chinese population.

[PMID 22159951] Polymorphisms of miRNAs genes are associated with the risk and prognosis of coronary artery disease.

[PMID 22426473] Lack of association of polymorphism in miRNA-196a2 with Parkinson's disease risk in a Chinese population.

[PMID 22539802] Impact of MiRSNPs on Survival and Progression in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplantation.


[PMID 22719192OA-icon.png] Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer


[PMID 23138850] miR-196a Overexpression and miR-196a2 Gene Polymorphism Are Prognostic Predictors of Oral Carcinomas


[PMID 23143626OA-icon.png] Hsa-miR-196a2 Functional SNP is Associated With Severe Toxicity After Platinum-Based Chemotherapy of Advanced Nonsmall Cell Lung Cancer Patients in a Chinese Population


[PMID 22818121] The prognostic impact of microRNA sequence polymorphisms on the recurrence of patients with completely resected non-small cell lung cancer


[PMID 23228090OA-icon.png] Evaluation of single nucleotide polymorphisms in microRNAs (hsa-miR-196a2 rs11614913 C/T) from Brazilian women with breast cancer


[PMID 23433405] A Single Nucleotide Polymorphism of miR-196a-2 and Vitiligo: An Association Study and Functional Analysis in a Han Chinese Population


[PMID 23470291] Association between Genetic Variants in Pre-MicroRNAs and Survival of Early-Stage NSCLC


[PMID 23516510OA-icon.png] Associations of pri-miR-34b/c and pre-miR-196a2 Polymorphisms and Their Multiplicative Interactions with Hepatitis B Virus Mutations with Hepatocellular Carcinoma Risk


[PMID 23219900OA-icon.png] Pre-microRNA variants predict HPV16-positive tumors and survival in patients with squamous cell carcinoma of the oropharynx


[PMID 23613771OA-icon.png] Polymorphisms of microRNA Sequences or Binding Sites and Lung Cancer: A Meta-Analysis and Systematic Review


[PMID 23728616] Association between genetic variants in pre-miRNA and colorectal cancer risk in a Chinese population


[PMID 23928854] A functional variant of pre-miRNA-196a2 confers risk for Behcet's disease but not for Vogt-Koyanagi-Harada syndrome or AAU in ankylosing spondylitis


[PMID 23791656] Three common functional polymorphisms in microRNA encoding genes in the susceptibility to hepatocellular carcinoma: a systematic review and meta-analysis


[PMID 24254303] Two functional polymorphisms in microRNAs and lung cancer risk: a meta-analysis


[PMID 24291415] Hsa-miR-196a2 polymorphism increases the risk of acute lymphoblastic leukemia in Chinese children


[PMID 24320161] Hsa-miR-196a2 functional SNP is associated with the risk of ESCC in individuals under 60 years old


[PMID 24413317OA-icon.png] MicroRNA sequence polymorphisms and the risk of different types of cancer


[PMID 24447667] A common variant in pre-miR-146 is associated with coronary artery disease risk and its mature miRNA expression


[PMID 24568449] Associations of Single Nucleotide Polymorphisms in miR-146a, miR-196a, miR-149 and miR-499 with Colorectal Cancer Susceptibility


[PMID 23001871] Association of the miR-146aC>G, miR-149T>C, miR-196a2T>C, and miR-499A>G polymorphisms with gastric cancer risk and survival in the Korean population.


[PMID 23160898] Quantitative assessment of the association between miR-196a2 rs11614913 polymorphism and gastrointestinal cancer risk.


[PMID 23423813] A functional polymorphism in MIR196A2 is associated with risk and prognosis of gastric cancer.


[PMID 23543085] Association study of genetic variants in miRNAs in patients with inflammatory bowel disease: preliminary results.


[PMID 23593385OA-icon.png] Effects of common polymorphism rs11614913 in Hsa-miR-196a2 on lung cancer risk.


[PMID 24039706OA-icon.png] The associations of single nucleotide polymorphisms in miR-146a, miR-196a and miR-499 with breast cancer susceptibility


[PMID 24916311] MicroRNAs related polymorphisms and genetic susceptibility to esophageal squamous cell carcinoma


[PMID 24922658] Genetic Polymorphism of miR-196a as a Prognostic Biomarker for Early Breast Cancer


[PMID 24972764] Polymorphism in microRNA-196a2 contributes to the risk of cardiovascular disease in type 2 diabetes patients


[PMID 24978643] Genetic variants of MicroRNA-related genes in susceptibility and prognosis of end-stage renal disease and renal allograft outcome among north Indians


[PMID 25213291] Genetic Polymorphisms in miRNAs and Susceptibility to Colorectal Cancer


[PMID 24681820] Genetic variations in microRNAs and the risk and survival of renal cell cancer


[PMID 25374621OA-icon.png] Common genetic variants in pre-microRNAs and risk of breast cancer in the North Indian population


[PMID 25445498] A common polymorphism in pre-miR-146a underlies Hirschsprung disease risk in Han Chinese


[PMID 25795117] Comprehensive assessment of the association between miRNA polymorphisms and gastric cancer risk


[PMID 25896941] miR-196a-2 rs11614913 polymorphism is associated with vitiligo by affecting heterodimeric molecular complexes of Tyr and Tyrp1


[PMID 25176041OA-icon.png] High-resolution melting analysis reveals genetic polymorphisms in microRNAs confer hepatocellular carcinoma risk in Chinese patients


[PMID 26112096] Assessment of association between genetic variants in microRNA genes hsa-miR-499, hsa-miR-196a2 and hsa-miR-27a and prostate cancer risk in Serbian population


[PMID 25557604] The association of common polymorphisms in miR-196a2 with waist to hip ratio and miR-1908 with serum lipid and glucose


[PMID 26305248OA-icon.png] Variants of MicroRNA Genes: Gender-Specific Associations with Multiple Sclerosis Risk and Severity


[PMID 26406571] The association between two common polymorphisms (miR-146a rs2910164 and miR-196a2 rs11614913) and susceptibility to gastric cancer: A meta-analysis


[PMID 26458899OA-icon.png] Common genetic polymorphisms in pre-microRNAs and risk of bladder cancer


[PMID 26518769] Genetic variants in miR-196a2 and miR-499 are associated with susceptibility to esophageal squamous cell carcinoma in Chinese Han population


[PMID 26537765] A Genetic Variant in Pre-miR-146a (rs2910164 C>G) Is Associated with the Decreased Risk of Acute Coronary Syndrome in a Chinese Population


[PMID 26554236] A Functional Single-Nucleotide Polymorphism in Pre-microRNA-196a2 is Associated with Atrial Fibrillation in Han Chinese


[PMID 26608782OA-icon.png] Association Between Single-Nucleotide Polymorphism (SNP) in miR-146a, miR-196a2, and miR-499 and Risk of Ischemic Stroke: A Meta-Analysis.


[PMID 26710106] Somatic Mutation of the SNP rs11614913 and Its Association with Increased MIR 196A2 Expression in Breast Cancer.


[PMID 26870188OA-icon.png] Association between the rs11614913 variant of miRNA-196a-2 and the risk of epithelial ovarian cancer.


[PMID 26886638OA-icon.png] The Associations of Single Nucleotide Polymorphisms in miR196a2, miR-499, and miR-608 With Breast Cancer Susceptibility: A STROBE-Compliant Observational Study.


[PMID 26926727] [Interaction research on smoking and microRNA genes SNP related to lung cancer in Fujian Han population].


[PMID 27173281] Association between the pre-miR-196a2 rs11614913 polymorphism and gastric cancer susceptibility in a Chinese population.


[PMID 27293850OA-icon.png] Effects of common polymorphisms in miR-146a and miR-196a2 on lung cancer susceptibility: a meta-analysis.


[PMID 27421647OA-icon.png] Association of single nucleotide polymorphisms in Pre-miR-27a, Pre-miR-196a2, Pre-miR-423, miR-608 and Pre-miR-618 with breast cancer susceptibility in a South American population.


[PMID 27509977] Combined Genotype Analyses of Precursor miRNA196a2 and 499a Variants with Hepatic and Renal Cancer Susceptibility a Preliminary Study.


[PMID 27701053OA-icon.png] MicroRNA-related polymorphisms and non-Hodgkin lymphoma susceptibility in the Multicenter AIDS Cohort Study.


[PMID 27796868] Effect of rs11614913 Polymorphism on Mature miR196a2 Expression and its Target Gene HOXC8 Expression in Human Glioma.


[PMID 27813602] Association of miR-196a2, miR-27a, and miR-499 polymorphisms with isolated congenital heart disease in a Chinese population.


[PMID 28301487OA-icon.png] Association of miR-196a-2 and miR-499 variants with ulcerative colitis and their correlation with expression of respective miRNAs.


[PMID 28922434] Association of microRNA Polymorphisms with the Risk of Gastric Cancer in a Romanian Population.


[PMID 28950676OA-icon.png] Association between Microrna 146a and Microrna 196a2 Genes Polymorphism and Breast Cancer Risk in North Indian Women


[PMID 28977965OA-icon.png] Genetic polymorphisms of non-coding RNAs associated with increased head and neck cancer susceptibility: a systematic review and meta-analysis.


[PMID 29715515] Contribution of microRNA-149, microRNA-146a, and microRNA-196a2 SNPs in colorectal cancer risk and clinicopathological features in Tunisia.


[PMID 30872409OA-icon.png] Impacts of Single Nucleotide Polymorphisms in three MicroRNAs (miR-146a, miR-196a2 and miR-499) on Susceptibility to Cervical Cancer among Indian Women.


[PMID 31472066] Micro-RNA 196a2 expression and miR-196a2 (rs11614913) polymorphism in T1DM: a pilot study.


[PMID 33230439OA-icon.png] miR-499 rs3746444 and miR-196a-2 rs11614913 Are Associated with the Risk of Glioma, but Not the Prognosis.