rs80359585

plus

Geno	Mag	Summary
(-;CTTAA)	6	BRCA2 variant considered pathogenic for breast cancer
(CTTAA;CTTAA)	0	common in clinvar
(TAACT;TAACT)	0	common in clinvar

Make rs80359585(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32340760

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359585
dbSNP (classic)	rs80359585
ClinGen	rs80359585
ebi	rs80359585
HLI	rs80359585
Exac	rs80359585
Gnomad	rs80359585
Varsome	rs80359585
LitVar	rs80359585
Map	rs80359585
PheGenI	rs80359585
Biobank	rs80359585
1000 genomes	rs80359585
hgdp	rs80359585
ensembl	rs80359585
geneview	rs80359585
scholar	rs80359585
google	rs80359585
pharmgkb	rs80359585
gwascentral	rs80359585
openSNP	rs80359585
23andMe	rs80359585
SNPshot	rs80359585
SNPdbe	rs80359585
MSV3d	rs80359585
GWAS Ctlg	rs80359585

Status

Merged into rs80359584

Max Magnitude

6

rs80359585, also known as 6633del5, c.6405_6409delCTTAA and p.Asn2135_Asn2137?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk
Alt
Reference	Rs80359585(TAACT;TAACT)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome not provided Hereditary cancer-predisposing syndrome Breast cancer
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome not provided Hereditary cancer-predisposing syndrome Breast cancer
Reversed	0
HGVS	NC_000013.10:g.32914897_32914901delCTTAA
CLNSRC	Breast Cancer Information Core (BRCA2) Inc.
CLNACC	RCV000031625.9, RCV000044934.7, RCV000160301.2, RCV000162930.3, RCV000240801.1,