rs80359584

plus

Geno	Mag	Summary
(-;CTTAA)	6	BRCA2 variant considered pathogenic for breast cancer
(-;TAACT)	6	BRCA2 variant considered pathogenic for breast cancer
(TAACT;TAACT)	0	common in clinvar

Make rs80359584(-;-)

Reference

GRCh38 38.1/142

Chromosome

13

Position

32340757

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359584
dbSNP (classic)	rs80359584
ClinGen	rs80359584
ebi	rs80359584
HLI	rs80359584
Exac	rs80359584
Gnomad	rs80359584
Varsome	rs80359584
LitVar	rs80359584
Map	rs80359584
PheGenI	rs80359584
Biobank	rs80359584
1000 genomes	rs80359584
hgdp	rs80359584
ensembl	rs80359584
geneview	rs80359584
scholar	rs80359584
google	rs80359584
pharmgkb	rs80359584
gwascentral	rs80359584
openSNP	rs80359584
23andMe	rs80359584
SNPshot	rs80359584
SNPdbe	rs80359584
MSV3d	rs80359584
GWAS Ctlg	rs80359584

Merged from

Rs80359585

Max Magnitude

6

rs80359584, also known as c.6405_6409delTAACT, 6630del5, c.6402_6406delTAACT and p.Asn2134_Leu2136?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359584(-;-) rs80359584(CTTAA;CTTAA)
Alt	rs80359584(-;-) rs80359584(CTTAA;CTTAA)
Reference	Rs80359584(TAACT;TAACT)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome not provided Hereditary cancer-predisposing syndrome Neoplasm of breast Familial cancer of breast
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome not provided Hereditary cancer-predisposing syndrome Neoplasm of breast Familial cancer of breast
Reversed	0
HGVS	NC_000013.10:g.32914897_32914901delCTTAA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031625.10, RCV000044934.8, RCV000160301.3, RCV000162930.3, RCV000240801.1, RCV000456954.1,