rs3780422
From SNPedia
Orientation | minus |
Stabilized | minus |
Make rs3780422(A;A) |
Make rs3780422(A;G) |
Make rs3780422(G;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 9 |
Position | 98380522 |
Gene | GABBR2 |
is a | snp |
is | mentioned by |
dbSNP | rs3780422 |
dbSNP (classic) | rs3780422 |
ClinGen | rs3780422 |
ebi | rs3780422 |
HLI | rs3780422 |
Exac | rs3780422 |
Gnomad | rs3780422 |
Varsome | rs3780422 |
LitVar | rs3780422 |
Map | rs3780422 |
PheGenI | rs3780422 |
Biobank | rs3780422 |
1000 genomes | rs3780422 |
hgdp | rs3780422 |
ensembl | rs3780422 |
geneview | rs3780422 |
scholar | rs3780422 |
rs3780422 | |
pharmgkb | rs3780422 |
gwascentral | rs3780422 |
openSNP | rs3780422 |
23andMe | rs3780422 |
SNPshot | rs3780422 |
SNPdbe | rs3780422 |
MSV3d | rs3780422 |
GWAS Ctlg | rs3780422 |
GMAF | 0.3903 |
Max Magnitude | 0 |
[PMID 15759211] Associated with nicotine Dependence as part of several haplotypes, based on a study of 1,000+ subjects including both African-Americans and European-Americans.
The risk haplotype varies between populations. Among African-Americans, the haplotype C-C-G of rs2491397-rs2184026-rs3750344 had a significant positive association with nicotine dependence. Among European-Americans, for rs1435252-rs3780422-rs2779562-rs3750344, the C-A-C-A haplotype was positively associated with nicotine dependence while the T-A-T-A haplotype was negatively associated.[PMID 15759211]