|(C;C)||2||1.8 times higher odds of having chronic hepatitis B|
|(T;T)||0||common in complete genomics|
[PMID 21346778] Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver
[PMID 21750111] A Genome-Wide Association Study of Chronic Hepatitis B Identified Novel Risk Locus in a Japanese Population
[PMID 22363396] HBV-Related Hepatocellular Carcinoma Susceptibility Gene KIF1B Is Not Associated with Development of Chronic Hepatitis B
[PMID 22448225] A Common HLA-DPA1 Variant Is Associated with Hepatitis B Virus Infection but Fails to Distinguish Active from Inactive Caucasian Carriers
[PMID 22543033] Relationship between HLA-DP gene polymorphisms and clearance of chronic hepatitis B virus infections: Case-control study and meta-analysis
[PMID 22536334] A Genome-Wide Homozygosity Association Study Identifies Runs of Homozygosity Associated with Rheumatoid Arthritis in the Human Major Histocompatibility Complex
[PMID 22105689] Genetic variants in HLA-DP/DQ influence both hepatitis B virus clearance and hepatocellular carcinoma development.
[PMID 22737229] Genome-Wide Association Study Confirming Association of HLA-DP with Protection against Chronic Hepatitis B and Viral Clearance in Japanese and Korean
[PMID 20436909] The textile plot: a new linkage disequilibrium display of multiple-single nucleotide polymorphism genotype data.
[PMID 21310144] Non-invasive screening of HLA-DPA1 and HLA-DPB1 alleles for persistent hepatitis B virus infection: susceptibility for vertical transmission and toward a personalized approach for vaccination and treatment.
[PMID 21402545] A common HLA-DPA1 variant is a major determinant of hepatitis B virus clearance in Han Chinese.
[PMID 21408128] Evaluation of genetic susceptibility loci for chronic hepatitis B in Chinese: two independent case-control studies.
[PMID 23326374] Host genetic factors affecting spontaneous HBsAg seroclearance in chronic hepatitis B patients
|Trait||Chronic hepatitis B infection|
|Title||A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.|
|Odds Ratio||1.89 [1.69-2.08]|
[PMID 24465836] Genetic association of human leukocyte antigens with chronicity or resolution of hepatitis B infection in thai population
[PMID 23428460] Genetic variants in HLA-DP/DQ contribute to risk of cervical cancer: a two-stage study in Chinese women.
[PMID 23449268] HLA-DP and IL28B polymorphisms: influence of host genome on hepatitis B surface antigen seroclearance in chronic hepatitis B.
[PMID 23601003] Association of the rs3077 and rs9277535 polymorphisms in HLA-DP with hepatitis B virus infection and spontaneous clearance: a meta-analysis.
[PMID 24897020] Genetic Variants in Human Leukocyte Antigen-DP Influence Both Hepatitis C Virus Persistence and Hepatitis C Virus F Protein Generation in the Chinese Han Population
[PMID 25802187] Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B
[PMID 25449085] [Studies on the association of single nucleotide polymorphisms of HLA-DP and DQ genes with the outcome of chronic hepatitis B virus infection]
[PMID 25376093] Association between single-nucleotide polymorphisms and early spontaneous hepatitis B virus e antigen seroconversion in children
[PMID 26387494] A randomized clinical trial of peginterferon alpha-2b with or without entecavir in patients with HBeAg-negative chronic hepatitis B: Role of host and viral factors associated with treatment response
[PMID 26634522] Relationship between HLA-DP gene polymorphisms and the risk of hepatocellular carcinoma: a meta-analysis.
[PMID 27252704] Relevance of HLA-DP/DQ and ICAM-1 SNPs among Ovarian Cancer Patients.
[PMID 27394003] Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China.
[PMID 28094303] Genetic Polymorphisms of rs3077 and rs9277535 in HLA-DP associated with Systemic lupus erythematosus in a Chinese population.
[PMID 28267888] Role of HLA-DP and HLA-DQ on the clearance of hepatitis B virus and the risk of chronic infection in a multiethnic population.