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rs1127354(A;A)

From SNPedia

Causative for ITPase deficiency; also, reduces risk of anemia due to ribivarin anti-hepatitis C virus therapy
Is agenotype
ofrs1127354
GeneITPA
Chromosome20
Position3,213,196
mentionedby
Magnitude3.2
ReputeBad
Geno Mag Summary
(A;A) 3.2 Causative for ITPase deficiency; also, reduces risk of anemia due to ribivarin anti-hepatitis C virus therapy
(A;C) 2 lower ITPA production; be aware if treated with mercaptopurine
(C;C) 0 common in clinvar

Causative for ITPase deficiency; be aware of higher neutropenia risk if treated with mercaptopurine; yet also, reduced risk of anemia when subject to ribivarin-based anti-hepatitis C virus therapy.