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Repute

From SNPedia

Repute: The opinion generally held of someone or something; the state of being generally regarded in a particular way.

Repute as a parameter is applied to a (single) genotype, and it can be either Good, Bad, or Not Set (blank).

'Good' and 'Bad' are mostly self explanatory. However, it's worth stating that many genotypes have a bit of good and a bit of bad. These and many other genotypes should remain 'Not Set'. Sometimes that's because they're not distinctly Good or Bad (like eye color) or Ancestry, but usually it means no human has come along to do the classification yet. Often this is the right thing to do, because the published studies are still too new and unreplicated to be convincing. However if you read through the literature and feel that a particular genotype is convincingly good or bad, please edit the genotype page so that future users can benefit from your insight.

In a Promethease report, the Repute is represented by the colors outlining each genotype. Genotypes with good, bad, and not set reputes are outlined in green, red, and gray, respectively.

Traits and similiar neutral concepts like eye color should be left blank.

See also the related concept Magnitude

Good things

 MagnitudeSummary
rs201011613(T;T)6.4Greatly reduced risk (~25 fold) for exfoliation syndrome
rs201011613(A;T)6.4Greatly reduced risk (~25 fold) for exfoliation syndrome
rs15793179(A;A)6normal, for chickens
rs372257803(C;T)5Lowered risk (0.6x) of coronary artery disease
rs398122987(-;AACT)5Lowered risk (0.6x) of coronary artery disease
rs398122988(-;CTCAA)5Lowered risk (0.6x) of coronary artery disease
rs267606655(CC;GA)5Lowered risk (0.6x) of coronary artery disease
rs121912617(G;G)5Short sleeper
i3003626(D;D)5resistant to HIV
rs11591147(T;T)4.52-3 fold lower risk of heart disease
... further results

Bad things

 MagnitudeSummary
i4000378(I;I)10BRCA1 (breast cancer) 5382insC
rs104894087(A;A)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs193922393(-;-)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs104894089(A;A)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs387907235(T;T)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs104894085(T;T)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs104894090(T;T)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs104894086(T;T)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs137852689(C;C)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
rs104894086(A;A)9.1Lipoid congenital adrenal hyperplasia (LCAH); treatment required
... further results