Gs315
From SNPedia
Gs315 | |
---|---|
Magnitude | 2 |
Repute | Good |
Summary | Reduced risk of PD in a haplotype with the C2 variant in the TF gene |
Criteria | Gs315/criteria |
A protective association was found (OR=0.83, 95% CI: 0.71-0.96) between Parkinson's Disease and a haplotype composed of the A allele at rs1880669 and the T allele at rs1049296 in transferrin (TF) in 1289 cases and 1391 controls [PMID 24121126]. Note that the SNP rs1049296 was found in combination with other iron SNPs to be related to an increased risk of AD in Gs293.