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User:JohnLloydScharf/Coronary Disease

From SNPedia

Coronary Disease[edit]


  • "rs2409722","8","11077226","GG" per the spittoon, the minor allele of this SNP (T) was associated with decreased triglycerides
http://www.snpedia.com/index.php/Rs2409722


  • "rs5186","3","149942678","AC" Rs5186(A;C) 1.5 ~1.4x increased risk of hypertension
http://www.snpedia.com/index.php/Rs5186


  • "rs1010","2","85662493","TT"=AA
Orientation minus
Genotype Effect
rs1010(A;A) normal form
rs1010(A;G) 1.75x risk of MI
rs1010(G;G) 1.75x risk of MI

Furthermore, this SNP is one of the 5 used by Celera's genetic risk score (GRS) for coronary heart disease (CHD).

  • "rs20455","6","39433056","AA" =TT
Orientation minus
rs20455, in the KIF6 gene. The risk allele (encoding the arginine at position 719) is rs20455(C).



  • "rs2383206","9","22105026","AG"
Genotype Effect
rs2383206(A;A) normal
rs2383206(A;G) 1.4x increased risk for heart disease
rs2383206(G;G) 1.7x increased risk for heart disease
http://www.snpedia.com/index.php/Rs2383206


  • rs2383207 9 22105959 AG
Genotype Effect
rs2383207(A;A) normal
rs2383207(A;G) increased risk for heart disease
rs2383207(G;G) increased risk for heart disease
http://www.snpedia.com/index.php/rs2383207


"rs10757274","9","22086055","AG"

  • Genotype Effect
rs10757274(A;A) normal
rs10757274(A;G) ~1.2x increased risk for heart disease
rs10757274(G;G) ~1.3x increased risk for heart disease
http://www.snpedia.com/index.php/Rs10757274


Rs10757278-Not Tested for by FTDNA

  • rs1333048 9 22115347 AC
Genotype Effect
rs1333048(A;A) normal
rs1333048(A;C) 1.3x increased coronary artery disease risk
rs1333048(C;C) 1.5x increased coronary artery disease risk; 2x increased periodontitis risk
http://www.snpedia.com/index.php/Rs1333048(A;C)


  • rs16847548 1 160301898 TT
Rs16847548(C;C) 2.5 2.6x increased risk for sudden cardiac death in Caucasians
Rs16847548(C;T) 1.3x increased risk for sudden cardiac death in Caucasians
Rs16847548(T;T) normal
http://www.snpedia.com/index.php/Rs16847548(T;T)


To Be Researched[edit]


http://www.snpedia.com/index.php/Rs1800629 "rs1800629","6","31651010","GG"