Promethease 0.1.82
Rs2383206
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs2383206 |
| hapmap | rs2383206 |
| hgdp | rs2383206 |
| ensembl | rs2383206 |
| gopubmed | rs2383206 |
| scholar | rs2383206 |
| rs2383206 | |
| pharmgkb | rs2383206 |
| hgvbaseg2p | rs2383206 |
| medrefsnp | rs2383206 |
| 23andMe | rs2383206 |
| SNP Nexus |
| Chromosome | 9 |
| Orientation | plus |
| Position | 22105026 |
| Genotype | Effect |
|---|---|
| rs2383206(A;A) | normal |
| rs2383206(A;G) | 1.4x increased risk for heart disease |
| rs2383206(G;G) | 1.7x increased risk for heart disease |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs2383206(A;A) | normal | |
| Rs2383206(A;G) | 1.4x increased risk for heart disease | |
| Rs2383206(G;G) | 33 | 1.7x increased risk for heart disease |
a blog post about investigating rs10757274 and rs2383206
| Neighbor | rs2383207 |
| Distance | 933 |
[PMID 18048766] This SNP was also associated with increased risk for coronary artery disease in a Korean population.
[PMID 18066490] Also found to be significant in a study of 416 Italian myocardial infarction patients.
A study of 1,000+ patients with early-onset angiographic coronary artery disease (CAD) concluded that rs2383206(G) was associated with an adjusted odds ratio of 1.39 (CI: 1.05-1.85) for (A;G) heterozygotes and 1.73 (CI: 1.26-2.37) for (G;G) homozygotes. This SNP alone accounted for 21% of the population attributable fraction and was independent of traditional risk factors, myocardial infarction risk, and the extent of disease.[PMID 19033013]
| ? | (A;A) (A;G) (G;G) |
|---|---|
|
| |
[PMID 19559344] Genetic variants on chromosome 9p21 and ischemic stroke in Chinese
[PMID 20031605] 9p21 is a Shared Susceptibility Locus Strongly for Coronary Artery Disease and Weakly for Ischemic Stroke in Chinese Han Population
