Rs2383206
| Orientation | plus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2383206 |
| PheGenI | rs2383206 |
| nextbio | rs2383206 |
| hapmap | rs2383206 |
| 1000 genomes | rs2383206 |
| hgdp | rs2383206 |
| ensembl | rs2383206 |
| gopubmed | rs2383206 |
| geneview | rs2383206 |
| scholar | rs2383206 |
| rs2383206 | |
| pharmgkb | rs2383206 |
| gwascentral | rs2383206 |
| openSNP | rs2383206 |
| 23andMe | rs2383206 |
| 23andMe all | rs2383206 |
| SNP Nexus | |
| SNPshot | rs2383206 |
| SNPdbe | rs2383206 |
| MSV3d | rs2383206 |
| Gene | CDKN2B-AS1 |
| Chromosome | 9 |
| Orientation | plus |
| GMAF | 0.4913 |
| Position | 22115026 |
| Reference | GRCh37.p5 37.3/137 |
| Max Magnitude | 3 |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | normal | |
| (A;G) | 2 | 1.4x increased risk for heart disease |
| (G;G) | 3 | 1.7x increased risk for heart disease |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
a blog post about investigating rs10757274 and rs2383206
| Neighbor | rs2383207 |
| Distance | 933 |
[PMID 18048766] This SNP was also associated with increased risk for coronary artery disease in a Korean population.
[PMID 18066490] Also found to be significant in a study of 416 Italian myocardial infarction patients.
A study of 1,000+ patients with early-onset angiographic coronary artery disease (CAD) concluded that rs2383206(G) was associated with an adjusted odds ratio of 1.39 (CI: 1.05-1.85) for (A;G) heterozygotes and 1.73 (CI: 1.26-2.37) for (G;G) homozygotes. This SNP alone accounted for 21% of the population attributable fraction and was independent of traditional risk factors, myocardial infarction risk, and the extent of disease.[PMID 19033013]
[PMID 19559344] Genetic variants on chromosome 9p21 and ischemic stroke in Chinese
[PMID 20031605] 9p21 is a Shared Susceptibility Locus Strongly for Coronary Artery Disease and Weakly for Ischemic Stroke in Chinese Han Population
[PMID 21375403] The Relationship Between Polymorphisms on Chromosome 9p21 and Age of Onset of Coronary Heart Disease in Black and White Women
[PMID 20718794] Association of polymorphisms in 9p21 region with CAD in North Indian population: replication of SNPs identified through GWAS
[PMID 21385355] Six sequence variants on chromosome 9p21.3 are associated with a positive family history of myocardial infarction: a multicenter registry
[PMID 22622453] The 9p21 coronary artery disease locus and kidney dysfunction in patients with Type 2 diabetes mellitus
[PMID 18362232] Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease.
[PMID 18443000] Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study.
[PMID 18505420] Four SNPS on chromosome 9p21 confer risk to premature, familial CAD and MI in an American Caucasian population (GeneQuest).
[PMID 18620593] Investigation of 89 candidate gene variants for effects on all-cause mortality following acute coronary syndrome.
[PMID 18704761] Molecular genetics of myocardial infarction.
[PMID 18757290] Associations between single nucleotide polymorphisms on chromosome 9p21 and risk of coronary heart disease in Chinese Han population.
[PMID 18957718] Chromosome 9p21.3 is associated with early-onset coronary heart disease in the Irish population.
[PMID 18987759] Genetic testing for atherosclerosis risk: inevitability or pipe dream?
[PMID 19033589] Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes.
[PMID 19173706] The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis.
[PMID 19329499] A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study.
[PMID 19379518] Development of a fingerprinting panel using medically relevant polymorphisms.
[PMID 19578366] Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
[PMID 19888323] Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.
[PMID 19956433] Genetics of coronary artery disease: focus on genome-wide association studies.
[PMID 19956784] Association of variation in the chromosome 9p21 locus with myocardial infarction versus chronic coronary artery disease.
[PMID 20386740] Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.
[PMID 20565774] Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project.
[PMID 23086272] Association between 9p21.3 genomic markers and coronary artery disease in East Asians: a meta-analysis involving 9,813 cases and 10,710 controls
[PMID 23134948] Association between 9p21 genetic variants and mortality risk in a prospective cohort of patients with type 2 diabetes (ZODIAC-15)
[PMID 23388737] Association of Single Nucleotide Polymorphisms on Chromosome 9p21.3 With Cardiovascular Death in Kidney Transplant Recipients
