SLC6A3

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23andMeSLC6A3
 GeneRIF     6531
 dbSNP        6531
 PubMed     6531
 SADR     6531
 HugeNav     6531
 HEFalMp     SLC6A3
Chromosome position Summary
Rs11564750 15007611,500,761
Rs2550948 15034431,503,443
Rs2617596 14997181,499,718
Rs2652511 14993881,499,388
Rs27048 14656441,465,644
Rs27072 14475211,447,521 Associated with increased susceptibility to alcohol withdrawal symptoms and ADHD.
Rs2963238 14974261,497,426
Rs2975226 14986151,498,615
Rs464049 14769041,476,904


The dopamine transporter SLC6A3 gene, also known as DAT1, has been studied in 250 alcohol-dependent Caucasian subjects. Of the 24% who exhibited withdrawal seizures, 4 DAT1 SNPs were associated with presence and severity of the seizures: DAT1-VNTR, rs27072, rs27048, and rs2963238.[PMID 18070248]