rs27048
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2x risk of severe alcohol withdrawal | |
| (C;T) | 0 | normal |
| (T;T) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 5 |
| Position | 1412530 |
| Gene | SLC6A3 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs27048 |
| dbSNP (classic) | rs27048 |
| ClinGen | rs27048 |
| ebi | rs27048 |
| HLI | rs27048 |
| Exac | rs27048 |
| Gnomad | rs27048 |
| Varsome | rs27048 |
| LitVar | rs27048 |
| Map | rs27048 |
| PheGenI | rs27048 |
| Biobank | rs27048 |
| 1000 genomes | rs27048 |
| hgdp | rs27048 |
| ensembl | rs27048 |
| geneview | rs27048 |
| scholar | rs27048 |
| rs27048 | |
| pharmgkb | rs27048 |
| gwascentral | rs27048 |
| openSNP | rs27048 |
| 23andMe | rs27048 |
| SNPshot | rs27048 |
| SNPdbe | rs27048 |
| MSV3d | rs27048 |
| GWAS Ctlg | rs27048 |
| GMAF | 0.3255 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[rs27048]], a SNP in the dopamine transporter SLC6A3 gene, has been associated with more severe symptoms upon alcohol withdrawal, such as seizures, in a study of 250 Caucasian alcohol-dependent patients. Two haplotypes appear to be tagged by this SNP and a neighbor, rs27072. [PMID 18070248]
Variations in the DAT1 gene may affect the inattentive subtype of ADHD.[PMID 20800641]
[PMID 16537431
] A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample.
