Rs27048
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs27048 |
| hapmap | rs27048 |
| hgdp | rs27048 |
| ensembl | rs27048 |
| gopubmed | rs27048 |
| scholar | rs27048 |
| rs27048 | |
| pharmgkb | rs27048 |
| hgvbaseg2p | rs27048 |
| medrefsnp | rs27048 |
| 23andMe | rs27048 |
| SNP Nexus |
| Gene | SLC6A3 |
| Chromosome | 5 |
| Orientation | plus |
| Position | 1465644 |
| Genotype | Effect |
|---|---|
| rs27048(C;C) | 2x risk of severe alcohol withdrawal |
| rs27048(C;T) | normal |
| rs27048(T;T) | normal |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs27048(C;C) | 2x risk of severe alcohol withdrawal | |
| Rs27048(C;T) | 00 | normal |
| Rs27048(T;T) | 00 | normal |
rs27048, a SNP in the dopamine transporter SLC6A3 gene, has been associated with more severe symptoms upon alcohol withdrawal, such as seizures, in a study of 250 Caucasian alcohol-dependent patients. Two haplotypes appear to be tagged by this SNP and a neighbor, rs27072. [PMID 18070248]
| ? | (C;C) (C;T) (T;T) |
|---|---|
|
| |
