From SNPedia
[
PMID 19198613] Each A at
rs965513 increased the odds of
thyroid cancer by 1.75 times. Each C at
rs944289 increased the odds of thyroid cancer by 1.37 times.
A genoset, Gs137, has also been created in SNPedia to represent the increased risk reported for carriers of both variants.
See also: spittoon
| ? | (C;C) (C;T) (T;T) |
|---|
 |
Related to THYROID CARCINOMA, FOLLICULAR; FTC
according to
omim 188470. See
also
| PharmGKB | PA164739982 |
| Name | |
| Annotation | GWAS results: Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. (Initial Sample Size: 192 cases, 37,196 controls; Replication Sample Size: 432 cases, 1,727 controls); (Region: 14q13.3; Reported Gene(s): NKX2-1; Risk Allele: rs944289-T); (p-value= 0.000000002).This variant is associated with Thyroid cancer. |
| Gene | - |
| Featue | |
| Evidence | PubMed ID:19198613; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Thyroid Neoplasms |
| Curation Level | Non-Curated |
