Rs965513

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is asnp
is mentioned by
dbSNPrs965513
hapmaprs965513
hgdprs965513
ensemblrs965513
gopubmedrs965513
scholarrs965513
googlers965513
pharmgkbrs965513
hgvbaseg2prs965513
medrefsnprs965513
23andMers965513
SNP Nexus

Chromosome9
Orientationplus
Position99595929
GenotypeEffect
rs965513(A;A)3.5x increased thyroid cancer risk
rs965513(A;G)1.7x increased thyroid cancer risk
rs965513(G;G)normal


Genotypes Magnitude Summary
Rs965513(A;A) 3.5x increased thyroid cancer risk
Rs965513(A;G) 1.7x increased thyroid cancer risk
Rs965513(G;G) normal
[PMID 19198613] Each A at rs965513 increased the odds of thyroid cancer by 1.75 times. Each C at rs944289 increased the odds of thyroid cancer by 1.37 times.

A genoset, Gs137, has also been created in SNPedia to represent the increased risk reported for carriers of both variants.

See also: spittoon

? (A;A) (A;G) (G;G)
Related to THYROID CARCINOMA, FOLLICULAR; FTC according to omim 188470. See also


Related to THYROID CARCINOMA, PAPILLARY according to omim 188550. See also


PharmGKBPA164739983
Name
AnnotationGWAS results: Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. (Initial Sample Size: 192 cases, 37,196 controls; Replication Sample Size: 432 cases, 1,727 controls); (Region: 9q22.33; Reported Gene(s): FOXE1; Risk Allele: rs965513-A); (p-value= 2E-27).This variant is associated with Thyroid cancer.
Gene-
Featue
EvidencePubMed ID:19198613; Web Resource:http://www.genome.gov/gwastudies/
Drugs
DiseasesThyroid Neoplasms
Curation LevelNon-Curated