Have questions? Visit https://www.reddit.com/r/SNPedia

Genoset

From SNPedia

A genoset refers to a defined set of genotypes; we have coined the term to represent the combination of alleles at 2 or more loci, especially when they are not contiguous along a chromosome. Typically, these are then related to a medical (or ancestral) consequence that arises only when a particular combination of SNPs is inherited.

Promethease understands this criteria syntax.

More information about genosets can be found in the related SNPedia blog post. Note that genosets themselves are boolean, not quantitative; each genoset is either true (present) or false (absent) in an individual, based on the genoset's criteria, in the same way that a genotype (or allele) is either present or absent. Note that if a DNA microarray platform lacks a given SNP, genosets that require it (that SNP) will not return a result during a Promethease evaluation.

Most Significant

 ReputeMagnitudeSummaryModification date
This property is a special property in this wiki.
Gs228Bad6sickle cell affected25 October 2012 02:21:38
Gs2676APOE1/APOE111 October 2013 05:15:46
Gs121Bad5DR3/4-DQ8 individual at high risk for type-1 diabetes21 October 2011 06:04:16
Gs2615Did you mix multiple people together?23 August 2015 19:00:17
Gs254Bad4.1Pseudocholinesterase Deficiency25 October 2012 02:24:20
Gs1454Female4 November 2015 13:26:25
Gs245Bad44x increased risk for esophageal squamous cell cancer among Han Chinese21 October 2011 06:04:36
Gs293Bad4increased risk of Alzheimer's disease, consider reducing iron levels29 May 2014 18:37:35
Gs1174risk of type-1 diabetes21 October 2011 06:04:12
Gs1134Haplogroup O38 January 2011 17:52:27
... further results


Most Recently Active

 ReputeMagnitudeSummaryModification date
This property is a special property in this wiki.
Gs187Bad2HLA-B*5801‎‎ homozygosity is possible. too common to be useful5 February 2016 11:19:08
Gs299Bad1.5Too common. Prone to Gout and possibly HLA-58015 February 2016 11:18:34
Gs186Bad1.5HLA-B*5801‎‎ heterozygosity is possible, unfortunately this is just too common to be useful5 February 2016 11:17:47
Gs221Bad2Autoimmune disorder risk in Europeans3 December 2015 01:02:54
Gs10322.5Mitochondrial Haplogroup H45 November 2015 03:04:42
Gs1454Female4 November 2015 13:26:25
Gs2662.5Data Quality Warning16 October 2015 21:25:57
Gs2615Did you mix multiple people together?23 August 2015 19:00:17
Gs123Bad22.7x increased basal cell carcinoma risk20 August 2015 00:35:40
Gs155Bad2.5CYP3A5 non-expressor23 July 2015 01:52:12
... further results


You can create a new genoset by clicking that link and filling in the form. But you'll still need to populate the criteria syntax.