From SNPedia
| Geno
|
Mag
|
Summary
|
| (A;A)
|
|
0.63x decreased risk for bipolar disorder
|
| (A;G)
|
|
0.68x decreased risk for bipolar disorder
|
| (G;G)
|
0
|
normal
|
| ? | (A;A) (A;G) (G;G) | 28 |
|---|
 |
, a SNP in the
FKBP5 gene, is associated with increased risk for
bipolar disorder in a study of 500+ Caucasian patients.
The most common allele, rs7757037(G), was associated with highest risk. Giving that allele a relative odds ratio of 1.0, the odds for the (A;G) and (A;A) genotypes were 0.68x (CI:0.53-0.87, p=0.007) and 0.63x (CI: 0.45-0.89, p=0.007).[PMID 18180755]
