Rs700651
From SNPedia
| Orientation | plus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs700651 |
| PheGenI | rs700651 |
| nextbio | rs700651 |
| hapmap | rs700651 |
| 1000 genomes | rs700651 |
| hgdp | rs700651 |
| ensembl | rs700651 |
| gopubmed | rs700651 |
| geneview | rs700651 |
| scholar | rs700651 |
| rs700651 | |
| pharmgkb | rs700651 |
| gwascentral | rs700651 |
| openSNP | rs700651 |
| 23andMe | rs700651 |
| 23andMe all | rs700651 |
| SNP Nexus | |
| SNPshot | rs700651 |
| SNPdbe | rs700651 |
| MSV3d | rs700651 |
| Gene | BOLL |
| Chromosome | 2 |
| Orientation | plus |
| GMAF | 0.3017 |
| Position | 198631714 |
| Reference | GRCh37 37.1/131 |
| Max Magnitude |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | normal | |
| (A;G) | ~1.18x increased risk of aneurysm | |
| (G;G) | ~1.56x increased risk of aneurysm |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
- rs700651 2 G 1.18x risk 1.56x risk
- rs10958409 8 A 1.37x risk 1.79x risk
- rs1333040 9 T 1.29x risk 1.67x risk
| GWAS snp | |
|---|---|
| PMID | [PMID 18997786] |
| Trait | Intracranial aneurysm |
| Title | Susceptibility loci for intracranial aneurysm in European and Japanese populations |
| Risk Allele | G |
| P-val | 4E-8 |
| Odds Ratio | 1.24 [1.15-1.34] |
[PMID 20395613] Confirmation of an association of single-nucleotide polymorphism rs1333040 on 9p21 with familial and sporadic intracranial aneurysms in Japanese patients.
| GET Evidence | |
|---|---|
| rs700651 | |
| aa_change | |
| aa_change_short | |
| impact | pathogenic |
| qualified_impact | Insufficiently evaluated pathogenic |
| overall_frequency | 0.714286 |
| summary | |
