Rs10958409

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Orientationplus
is asnp
is mentioned by
dbSNPrs10958409
PheGenIrs10958409
nextbiors10958409
hapmaprs10958409
1000 genomesrs10958409
hgdprs10958409
ensemblrs10958409
gopubmedrs10958409
geneviewrs10958409
scholarrs10958409
googlers10958409
pharmgkbrs10958409
gwascentralrs10958409
openSNPrs10958409
23andMers10958409
23andMe allrs10958409
SNP Nexus

SNPshotrs10958409
SNPdbers10958409
MSV3drs10958409
Chromosome8
Orientationplus
GMAF0.2163
Position55327091
ReferenceGRCh37 37.1/131
Max Magnitude0
Geno Mag Summary
(A;A) 1.79x increased aneurysm risk
(A;G) 1.37x increased aneurysm risk
(G;G) 0 normal
? (A;A) (A;G) (G;G) 28
23andMe blog aneurysm
  • rs700651 2 G 1.18x risk 1.56x risk
  • rs10958409 8 A 1.37x risk 1.79x risk
  • rs1333040 9 T 1.29x risk 1.67x risk
GWAS snp
PMID [PMID 18997786OA-icon.png]
Trait Intracranial aneurysm
Title Susceptibility loci for intracranial aneurysm in European and Japanese populations
Risk Allele A
P-val 1E-10
Odds Ratio 1.36 [1.24-1.49]
OMIM612587
DescANEURYSM, INTRACRANIAL BERRY, 10
Variant
Relatedalso
[PMID 20190001OA-icon.png] The Relationship Between Smoking and Replicated Sequence Variants on Chromosomes 8 and 9 With Familial Intracranial Aneurysm


[PMID 20395613] Confirmation of an association of single-nucleotide polymorphism rs1333040 on 9p21 with familial and sporadic intracranial aneurysms in Japanese patients.


GET Evidence
rs10958409
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.210938
summary



Brain Aneurysm


[PMID 22476622] Increased risk of stroke in oral contraceptive users carried replicated genetic variants: a population-based case-control study in China.


[PMID 23733552] Genetic risk factors for intracranial aneurysms: a meta-analysis in more than 116,000 individuals.