Rs10958409
From SNPedia
| Orientation | plus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10958409 |
| PheGenI | rs10958409 |
| nextbio | rs10958409 |
| hapmap | rs10958409 |
| 1000 genomes | rs10958409 |
| hgdp | rs10958409 |
| ensembl | rs10958409 |
| gopubmed | rs10958409 |
| geneview | rs10958409 |
| scholar | rs10958409 |
| rs10958409 | |
| pharmgkb | rs10958409 |
| gwascentral | rs10958409 |
| openSNP | rs10958409 |
| 23andMe | rs10958409 |
| 23andMe all | rs10958409 |
| SNP Nexus | |
| SNPshot | rs10958409 |
| SNPdbe | rs10958409 |
| MSV3d | rs10958409 |
| Chromosome | 8 |
| Orientation | plus |
| GMAF | 0.2166 |
| Position | 55327091 |
| Reference | GRCh37 37.1/131 |
| Max Magnitude | 0 |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 1.79x increased aneurysm risk | |
| (A;G) | 1.37x increased aneurysm risk | |
| (G;G) | 0 | normal |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
- rs700651 2 G 1.18x risk 1.56x risk
- rs10958409 8 A 1.37x risk 1.79x risk
- rs1333040 9 T 1.29x risk 1.67x risk
| GWAS snp | |
|---|---|
| PMID | [PMID 18997786] |
| Trait | Intracranial aneurysm |
| Title | Susceptibility loci for intracranial aneurysm in European and Japanese populations |
| Risk Allele | A |
| P-val | 1E-10 |
| Odds Ratio | 1.36 [1.24-1.49] |
[PMID 20190001] The Relationship Between Smoking and Replicated Sequence Variants on Chromosomes 8 and 9 With Familial Intracranial Aneurysm
[PMID 20395613] Confirmation of an association of single-nucleotide polymorphism rs1333040 on 9p21 with familial and sporadic intracranial aneurysms in Japanese patients.
| GET Evidence | |
|---|---|
| rs10958409 | |
| aa_change | |
| aa_change_short | |
| impact | pathogenic |
| qualified_impact | Insufficiently evaluated pathogenic |
| overall_frequency | 0.210938 |
| summary | |
