Rs6449213

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Orientationplus
is asnp
is mentioned by
dbSNPrs6449213
PheGenIrs6449213
nextbiors6449213
hapmaprs6449213
1000 genomesrs6449213
hgdprs6449213
ensemblrs6449213
gopubmedrs6449213
geneviewrs6449213
scholarrs6449213
googlers6449213
pharmgkbrs6449213
gwascentralrs6449213
openSNPrs6449213
23andMers6449213
23andMe allrs6449213
SNP Nexus

SNPshotrs6449213
SNPdbers6449213
MSV3drs6449213
GeneSLC2A9
Chromosome4
Orientationplus
GMAF0.1299
Position9992591
ReferenceGRCh38 38.1/141
Max Magnitude2
Geno Mag Summary
(C;C) 2 ~4x higher risk for hyperuracemia
(C;T) ~2x higher risk for hyperuracemia
(T;T) 0 normal
? (C;C) (C;T) (T;T) 28

This is basically a surrogate for rs7442295, and thus associated with higher serum urate levels.

OMIM612076
DescHYPOURICEMIA, RENAL, 2; RHUC2
Variant
Relatedalso
OMIM606142
DescSOLUTE CARRIER FAMILY 2 (FACILITATED GLUCOSE TRANSPORTER), MEMBER
Variant
Relatedalso


[PMID 20589538] Variation in the Uric Acid Transporter Gene SLC2A9 and Its Association with AAO of Parkinson's Disease

OMIM606142
Desc
Variant0002
Relatedalso
[PMID 18179892OA-icon.png] Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.


[PMID 18398472OA-icon.png] Association of common polymorphisms in GLUT9 gene with gout but not with coronary artery disease in a large case-control study.


[PMID 18487473OA-icon.png] Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI.


[PMID 18606621OA-icon.png] SLC2A9--a fructose transporter identified as a novel uric acid transporter.


[PMID 18834626OA-icon.png] Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.


[PMID 19260141OA-icon.png] Genome-wide association study of biochemical traits in Korcula Island, Croatia.


[PMID 20053405OA-icon.png] Sex and age interaction with genetic association of atherogenic uric acid concentrations.


[PMID 20162742OA-icon.png] Predictive value of 8 genetic loci for serum uric acid concentration.


[PMID 20162743OA-icon.png] Common variants in SLC17A3 gene affect intra-personal variation in serum uric acid levels in longitudinal time series.


[PMID 20162744OA-icon.png] Interactions between genetic variants in glucose transporter type 9 (SLC2A9) and dietary habits in serum uric acid regulation.


[PMID 20162745OA-icon.png] Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients.


[PMID 20348110OA-icon.png] Bayesian methods for instrumental variable analysis with genetic instruments ('Mendelian randomization'): example with urate transporter SLC2A9 as an instrumental variable for effect of urate levels on metabolic syndrome.


[PMID 21294900OA-icon.png] A genome-wide association study of serum uric acid in African Americans.

GWAS snp
PMID [PMID 23703922OA-icon.png]
Trait Uric acid levels
Title A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.
Risk Allele
P-val 3E-12
Odds Ratio NR NR