From SNPedia
rs4570625, also known as G-703T, is a SNP in the tryptophan hydroxylase 2
TPH2 gene. This SNP has been linked to several psychiatric and/or behavioural phenomena, including:
- rs4570625 and rs11178997 in TPH2's regulatory region display preferential transmission
- [PMID 19052197] rs4570625(G;G) homozygosity was a significant predictor of clinical placebo response, being associated with greater improvement in anxiety symptoms.
g2b2mh is rs4570625(G;G) is a significant predictor of clinical placebo response? maybe not
[PMID 19132526] panic disorder with a possible gender-dependent effect
| ? | (G;G) (G;T) (T;T) |
|---|
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Related to ATTENTION DEFICIT-HYPERACTIVITY DISORDER; ADHD
according to
omim 143465. See
also
Related to TRYPTOPHAN HYDROXYLASE 2; TPH2
according to
omim 607478. See
also
[PMID 19894072] A gene-environment investigation on personality traits in two independent clinical sets of adult patients with personality disorder and attention deficit/hyperactive disorder
[PMID 18427560] Tph2 gene variants modulate response control processes in adult ADHD patients and healthy individuals
