MEIS1

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 HEFalMp     MEIS1
Chromosome position Summary
Rs12469063 6661781166,617,811
Rs2300478 6663495666,634,956
Rs6710341 6661192566,611,925


The MEIS1 gene is most likely important in development, but it's functions remain unclear. Several SNPs in the MEIS1 gene, and in particular one haplotype, have been associated with increased risk for restless legs syndrome. [PMID 17637780]

These SNPs and haplotype are:

The association from this region that gives the highest association to restless legs syndrome is the haplotype consisting of the rs6710341(A) and rs12469063(G) alleles. This haplotype gives rise to an odds ratio of 2.75 (CI: 2.23-3.41). [PMID 17637780]