APOA5
From SNPedia
| is a | gene |
| is | mentioned by |
| wikipedia | APOA5 |
| APOA5 | |
| gopubmed | APOA5 |
| 23andMe | APOA5 |
dbSNP 116519
PubMed 116519
SADR 116519
HugeNav 116519
HEFalMp APOA5
| Chromosome position | Summary | |
|---|---|---|
| Rs2075291 | 116166601116,166,601 | |
| Rs3135506 | 116167616116,167,616 | |
| Rs662799 | 116168916116,168,916 |
SNPs in the apolipoprotein A-V gene, APOA5, have primarily been associated with plasma lipoprotein levels and associated downstream consequences, such as weight gain and heart disease risk.
Significant SNPs of APOA5 include:
- rs2075291: Associated with high triglyceride levels in Asians.
- rs662799 :
- In [PMID 16682041] 13% of the population have rs662799 -1131T>C which prevents weight gain from high fat diets.
- In [PMID 17211608] rs662799 -1131T>C in APOA5 is present in approximately 13% of this population, modulates the effect of fat intake on BMI and obesity risk in both men and women.
- Misc. (awaiting categorization):
- dbsnp
- S19W is also known as rs3135506
- [PMID 16943456]
- [PMID 16957409] 2 SNPs
- [PMID 16474174] Variants in the gene APOA5 are associated with carotid atherosclerosis, and modification by obesity: the Framingham Study.
