|?|| (A;A) (A;G) (G;G) ||28|
Each G allele is associated with 0.89 x odds of high blood pressure, according to 23andMe. [PMID 19430483]
23andMe blog blood pressure
||Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
||0.5340 [0.40-0.66] mmHg decrease
[PMID 19944404] Genomic dissection of population substructure of Han Chinese and its implication in association studies.
[PMID 20031578] Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.
[PMID 20852445] Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans.
[PMID 22504314] Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.
[PMID 22525200] Pharmacogenetic implications for eight common blood pressure-associated single-nucleotide polymorphisms.
High Blood Pressure (Hypertension)
[PMID 22959498] Recapitulation of four hypertension susceptibility genes (CSK, CYP17A1, MTHFR, and FGF5) in East Asians.
[PMID 27755385] The antihypertensive MTHFR gene polymorphism rs17367504-G is a possible novel protective locus for preeclampsia.
[PMID 28425437] Are genetic polymorphisms in the renin-angiotensin-aldosterone system associated with essential hypertension? Evidence from genome-wide association studies.