|| 1.2x increased risk for schizophrenia
|| 1.4x increased risk for schizophrenia
|?|| (A;A) (A;C) (C;C) ||28|
23andMe blog schizophrenia
- rs3131296(C) increased the odds of schizophrenia by 1.19x
- rs12807809(T) increased the odds of schizophrenia by 1.15x
- rs9960767(C) increased the odds of schizophrenia by 1.23 times.
] The Schizophrenia Risk Allele C of the TCF4 rs9960767 Polymorphism Disrupts Sensorimotor Gating in Schizophrenia Spectrum and Healthy Volunteers
[PMID 21812098] Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain
[PMID 22451930] Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating
[PMID 20485477] New Genetic Findings in Schizophrenia: Is there Still Room for the Dopamine Hypothesis of Schizophrenia?
[PMID 21228604] Novel schizophrenia risk gene TCF4 influences verbal learning and memory functioning in schizophrenia patients.
[PMID 21932083] Impact of TCF4 on the genetics of schizophrenia.
|| Insufficiently evaluated pathogenic
[PMID 22005930] Genome-wide association study of Alzheimer's disease with psychotic symptoms.
[PMID 27305091] Genetic Association of TCF4 and AKT1 Gene Variants with the Age at Onset of Schizophrenia.