rs876658211

plus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;A)	6	Possible miscall by 23andMe; otherwise: Lynch syndrome, pathogenic mutation

Make rs876658211(A;A)

Reference

GRCh38.p2 38.2/147

Chromosome

2

Position

47482824

Gene

MSH2

is a	snp
is	mentioned by
dbSNP	rs876658211
dbSNP (classic)	rs876658211
ClinGen	rs876658211
ebi	rs876658211
HLI	rs876658211
Exac	rs876658211
Gnomad	rs876658211
Varsome	rs876658211
LitVar	rs876658211
Map	rs876658211
PheGenI	rs876658211
Biobank	rs876658211
1000 genomes	rs876658211
hgdp	rs876658211
ensembl	rs876658211
geneview	rs876658211
scholar	rs876658211
google	rs876658211
pharmgkb	rs876658211
gwascentral	rs876658211
openSNP	rs876658211
23andMe	rs876658211
SNPshot	rs876658211
SNPdbe	rs876658211
MSV3d	rs876658211
GWAS Ctlg	rs876658211

Max Magnitude

6

aka c.2680dupA

considered pathogenic for hereditary cancer-predisposing syndrome (presumably equivalent to Lynch syndrome) in ClinVar; one of the most frequent MSH2 gene mutations noted in gnomAD

23andMe name: i5037796

ClinVar
Risk	rs876658211(A;A)
Alt	rs876658211(A;A)
Reference	Rs876658211(-;-)
Significance	Pathogenic
Disease	Hereditary cancer-predisposing syndrome
Variation	info
Gene	MSH2
CLNDBN	Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000002.11:g.47709963dupA
CLNSRC
CLNACC	RCV000214664.1,