rs80359645

plus

Geno	Mag	Summary
(-;TGAT)	6	BRCA2 variant considered pathogenic for breast cancer
(TGAT;TGAT)	0	common in clinvar

Make rs80359645(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32330966

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359645
dbSNP (classic)	rs80359645
ClinGen	rs80359645
ebi	rs80359645
HLI	rs80359645
Exac	rs80359645
Gnomad	rs80359645
Varsome	rs80359645
LitVar	rs80359645
Map	rs80359645
PheGenI	rs80359645
Biobank	rs80359645
1000 genomes	rs80359645
hgdp	rs80359645
ensembl	rs80359645
geneview	rs80359645
scholar	rs80359645
google	rs80359645
pharmgkb	rs80359645
gwascentral	rs80359645
openSNP	rs80359645
23andMe	rs80359645
SNPshot	rs80359645
SNPdbe	rs80359645
MSV3d	rs80359645
GWAS Ctlg	rs80359645

Max Magnitude

6

rs80359645, also known as 957del4, c.729_732delTGAT and p.Asn243_Asp244?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359645(-;-)
Alt	rs80359645(-;-)
Reference	Rs80359645(TGAT;TGAT)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32905103_32905106delTGAT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000045180.4, RCV000077400.5, RCV000162898.1, RCV000482942.1,