rs80359578

plus

Geno	Mag	Summary
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80359578(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32340728

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359578
dbSNP (classic)	rs80359578
ClinGen	rs80359578
ebi	rs80359578
HLI	rs80359578
Exac	rs80359578
Gnomad	rs80359578
Varsome	rs80359578
LitVar	rs80359578
Map	rs80359578
PheGenI	rs80359578
Biobank	rs80359578
1000 genomes	rs80359578
hgdp	rs80359578
ensembl	rs80359578
geneview	rs80359578
scholar	rs80359578
google	rs80359578
pharmgkb	rs80359578
gwascentral	rs80359578
openSNP	rs80359578
23andMe	rs80359578
SNPshot	rs80359578
SNPdbe	rs80359578
MSV3d	rs80359578
GWAS Ctlg	rs80359578

Max Magnitude

6

rs80359578, also known as 6601delA, c.6373_6373delA and p.Thr2125Profs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359578(-;-)
Alt	rs80359578(-;-)
Reference	Rs80359578(A;A)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer not provided
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 not provided
Reversed	0
HGVS	NC_000013.10:g.32914865delA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044925.2, RCV000077372.5, RCV000217749.2,