rs80359433

plus

Geno	Mag	Summary
(-;T)	6	BRCA2 variant considered pathogenic for breast cancer
(-;TT)	6	BRCA2 variant considered pathogenic for breast cancer
(T;T)	0	common in clinvar

Make rs80359433(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32338524

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359433
dbSNP (classic)	rs80359433
ClinGen	rs80359433
ebi	rs80359433
HLI	rs80359433
Exac	rs80359433
Gnomad	rs80359433
Varsome	rs80359433
LitVar	rs80359433
Map	rs80359433
PheGenI	rs80359433
Biobank	rs80359433
1000 genomes	rs80359433
hgdp	rs80359433
ensembl	rs80359433
geneview	rs80359433
scholar	rs80359433
google	rs80359433
pharmgkb	rs80359433
gwascentral	rs80359433
openSNP	rs80359433
23andMe	rs80359433
SNPshot	rs80359433
SNPdbe	rs80359433
MSV3d	rs80359433
GWAS Ctlg	rs80359433

Max Magnitude

6

rs80359433, also known as c.4168_4169delTT, c.4169dupT, 4397delT, c.4169delT and p.Leu1390Trpfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar. All forms are considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359433(-;-)
Alt	rs80359433(-;-)
Reference	Rs80359433(T;T)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2
Reversed	0
HGVS	NC_000013.10:g.32912661delT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044364.2, RCV000113282.3,