rs80359380

plus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;T)	6	BRCA2 variant considered pathogenic for breast cancer
(-;TT)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs80359380(T;T)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32337619

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359380
dbSNP (classic)	rs80359380
ClinGen	rs80359380
ebi	rs80359380
HLI	rs80359380
Exac	rs80359380
Gnomad	rs80359380
Varsome	rs80359380
LitVar	rs80359380
Map	rs80359380
PheGenI	rs80359380
Biobank	rs80359380
1000 genomes	rs80359380
hgdp	rs80359380
ensembl	rs80359380
geneview	rs80359380
scholar	rs80359380
google	rs80359380
pharmgkb	rs80359380
gwascentral	rs80359380
openSNP	rs80359380
23andMe	rs80359380
SNPshot	rs80359380
SNPdbe	rs80359380
MSV3d	rs80359380
GWAS Ctlg	rs80359380

Max Magnitude

6

rs80359380, also known as 3492insT, c.3264_3265insT, c.3264dupT and p.Pro1088_Gln1089?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

23andMe name: i5010497

ClinVar
Risk	rs80359380(T;T) rs80359380(TT;TT)
Alt	rs80359380(T;T) rs80359380(TT;TT)
Reference	Rs80359380(-;-)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32911756_32911757insTT; NC_000013.10:g.32911756dupT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044162.2, RCV000031411.8, RCV000044163.6, RCV000131493.3, RCV000203627.3, RCV000459431.1,