rs80359370

plus

Geno	Mag	Summary
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80359370(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32337501

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359370
ClinGen	rs80359370
ebi	rs80359370
HLI	rs80359370
Exac	rs80359370
Varsome	rs80359370
Map	rs80359370
PheGenI	rs80359370
hapmap	rs80359370
1000 genomes	rs80359370
hgdp	rs80359370
ensembl	rs80359370
gopubmed	rs80359370
geneview	rs80359370
scholar	rs80359370
google	rs80359370
pharmgkb	rs80359370
gwascentral	rs80359370
openSNP	rs80359370
23andMe	rs80359370
23andMe all	rs80359370
SNP Nexus
SNPshot	rs80359370
SNPdbe	rs80359370
MSV3d	rs80359370
GWAS Ctlg	rs80359370

Max Magnitude

6

rs80359370, also known as 3374delA, c.3146_3146delA and p.Asn1049Ilefs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk
Alt
Reference	Rs80359370(A;A)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2
Reversed	0
HGVS	NC_000013.10:g.32911638delA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044125.2, RCV000113140.3,