rs80359358

plus

Geno	Mag	Summary
(-;G)	6	BRCA2 variant considered pathogenic for breast cancer
(G;G)	0	common in clinvar

Make rs80359358(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32337191

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359358
dbSNP (classic)	rs80359358
ClinGen	rs80359358
ebi	rs80359358
HLI	rs80359358
Exac	rs80359358
Gnomad	rs80359358
Varsome	rs80359358
LitVar	rs80359358
Map	rs80359358
PheGenI	rs80359358
Biobank	rs80359358
1000 genomes	rs80359358
hgdp	rs80359358
ensembl	rs80359358
geneview	rs80359358
scholar	rs80359358
google	rs80359358
pharmgkb	rs80359358
gwascentral	rs80359358
openSNP	rs80359358
23andMe	rs80359358
SNPshot	rs80359358
SNPdbe	rs80359358
MSV3d	rs80359358
GWAS Ctlg	rs80359358

Max Magnitude

6

rs80359358, also known as 3064delG, c.2836_2836delG and p.Asp946Ilefs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359358(-;-)
Alt	rs80359358(-;-)
Reference	Rs80359358(G;G)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer not provided
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 not provided
Reversed	0
HGVS	NC_000013.10:g.32911328delG
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044072.3, RCV000113102.3, RCV000480163.1,