rs80359355

plus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;TT)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs80359355(TT;TT)

Reference

GRCh38 38.1/142

Chromosome

13

Position

32337188

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359355
dbSNP (classic)	rs80359355
ClinGen	rs80359355
ebi	rs80359355
HLI	rs80359355
Exac	rs80359355
Gnomad	rs80359355
Varsome	rs80359355
LitVar	rs80359355
Map	rs80359355
PheGenI	rs80359355
Biobank	rs80359355
1000 genomes	rs80359355
hgdp	rs80359355
ensembl	rs80359355
geneview	rs80359355
scholar	rs80359355
google	rs80359355
pharmgkb	rs80359355
gwascentral	rs80359355
openSNP	rs80359355
23andMe	rs80359355
SNPshot	rs80359355
SNPdbe	rs80359355
MSV3d	rs80359355
GWAS Ctlg	rs80359355

Max Magnitude

6

rs80359355, also known as 3061insTT, c.2833_2834insTT and p.Lys945?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359355(TT;TT)
Alt	rs80359355(TT;TT)
Reference	Rs80359355(-;-)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32911325_32911326insTT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000113098.3, RCV000216259.1,