rs80359322

plus

Geno	Mag	Summary
(-;C)	6	BRCA2 variant considered pathogenic for breast cancer
(C;C)	0	common in clinvar

Make rs80359322(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32336447

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359322
dbSNP (classic)	rs80359322
ClinGen	rs80359322
ebi	rs80359322
HLI	rs80359322
Exac	rs80359322
Gnomad	rs80359322
Varsome	rs80359322
LitVar	rs80359322
Map	rs80359322
PheGenI	rs80359322
Biobank	rs80359322
1000 genomes	rs80359322
hgdp	rs80359322
ensembl	rs80359322
geneview	rs80359322
scholar	rs80359322
google	rs80359322
pharmgkb	rs80359322
gwascentral	rs80359322
openSNP	rs80359322
23andMe	rs80359322
SNPshot	rs80359322
SNPdbe	rs80359322
MSV3d	rs80359322
GWAS Ctlg	rs80359322

Max Magnitude

6

rs80359322, also known as 2320delC, c.2092_2092delC and p.Leu698Tyrfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359322(-;-)
Alt	rs80359322(-;-)
Reference	Rs80359322(C;C)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary cancer-predisposing syndrome not provided Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome not provided Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32910584delC
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031355.6, RCV000166692.1, RCV000212218.2, RCV000221559.2,