rs80359302

plus

Geno	Mag	Summary
(-;GAAAA)	6	BRCA2 variant considered pathogenic for breast cancer
(AAAAG;AAAAG)	0	common in clinvar
(GAAAA;GAAAA)	0	common in clinvar

Make rs80359302(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32333233

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359302
dbSNP (classic)	rs80359302
ClinGen	rs80359302
ebi	rs80359302
HLI	rs80359302
Exac	rs80359302
Gnomad	rs80359302
Varsome	rs80359302
LitVar	rs80359302
Map	rs80359302
PheGenI	rs80359302
Biobank	rs80359302
1000 genomes	rs80359302
hgdp	rs80359302
ensembl	rs80359302
geneview	rs80359302
scholar	rs80359302
google	rs80359302
pharmgkb	rs80359302
gwascentral	rs80359302
openSNP	rs80359302
23andMe	rs80359302
SNPshot	rs80359302
SNPdbe	rs80359302
MSV3d	rs80359302
GWAS Ctlg	rs80359302

Max Magnitude

6

rs80359302, also known as 1983del5, c.1755_1759delGAAAA and p.Lys585_Thr587?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359302(-;-)
Alt	rs80359302(-;-)
Reference	Rs80359302(AAAAG;AAAAG)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32907370_32907374delGAAAA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031335.7, RCV000074514.7, RCV000131055.4, RCV000212215.2,