rs80359297

plus

Geno	Mag	Summary
(-;T)	6	BRCA2 variant considered pathogenic for breast cancer
(T;T)	0	common in clinvar

Make rs80359297(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32333132

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359297
dbSNP (classic)	rs80359297
ClinGen	rs80359297
ebi	rs80359297
HLI	rs80359297
Exac	rs80359297
Gnomad	rs80359297
Varsome	rs80359297
LitVar	rs80359297
Map	rs80359297
PheGenI	rs80359297
Biobank	rs80359297
1000 genomes	rs80359297
hgdp	rs80359297
ensembl	rs80359297
geneview	rs80359297
scholar	rs80359297
google	rs80359297
pharmgkb	rs80359297
gwascentral	rs80359297
openSNP	rs80359297
23andMe	rs80359297
SNPshot	rs80359297
SNPdbe	rs80359297
MSV3d	rs80359297
GWAS Ctlg	rs80359297

Max Magnitude

6

rs80359297, also known as 1882delT, c.1654_1654delT and p.Ser552Profs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359297(-;-)
Alt	rs80359297(-;-)
Reference	Rs80359297(T;T)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32907269delT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000043855.3, RCV000077260.5, RCV000130097.3,