rs80359270

plus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs80359270(A;A)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32332711

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359270
dbSNP (classic)	rs80359270
ClinGen	rs80359270
ebi	rs80359270
HLI	rs80359270
Exac	rs80359270
Gnomad	rs80359270
Varsome	rs80359270
LitVar	rs80359270
Map	rs80359270
PheGenI	rs80359270
Biobank	rs80359270
1000 genomes	rs80359270
hgdp	rs80359270
ensembl	rs80359270
geneview	rs80359270
scholar	rs80359270
google	rs80359270
pharmgkb	rs80359270
gwascentral	rs80359270
openSNP	rs80359270
23andMe	rs80359270
SNPshot	rs80359270
SNPdbe	rs80359270
MSV3d	rs80359270
GWAS Ctlg	rs80359270

Max Magnitude

6

rs80359270, also known as 1461insA, c.1233_1234insA and p.Ile411_Pro412?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359270(A;A)
Alt	rs80359270(A;A)
Reference	Rs80359270(-;-)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2
Reversed	0
HGVS	NC_000013.10:g.32906848dupA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000043763.2, RCV000112898.3,