rs80358789

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;C)	6	BRCA2 variant considered pathogenic for breast cancer
(C;C)	0	common in clinvar

Make rs80358789(A;A)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32340010

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80358789
dbSNP (classic)	rs80358789
ClinGen	rs80358789
ebi	rs80358789
HLI	rs80358789
Exac	rs80358789
Gnomad	rs80358789
Varsome	rs80358789
LitVar	rs80358789
Map	rs80358789
PheGenI	rs80358789
Biobank	rs80358789
1000 genomes	rs80358789
hgdp	rs80358789
ensembl	rs80358789
geneview	rs80358789
scholar	rs80358789
google	rs80358789
pharmgkb	rs80358789
gwascentral	rs80358789
openSNP	rs80358789
23andMe	rs80358789
SNPshot	rs80358789
SNPdbe	rs80358789
MSV3d	rs80358789
GWAS Ctlg	rs80358789

Max Magnitude

6

rs80358789, also known as C1885X, c.5655C>A and p.Cys1885Ter, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80358789(A;A)
Alt	rs80358789(A;A)
Reference	Rs80358789(C;C)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome not provided Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome not provided Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32914147C>A
CLNSRC	ClinVar
CLNACC	RCV000031566.7, RCV000044709.3, RCV000160093.3, RCV000220539.1,