rs80357884

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(-;A)	6	BRCA1 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80357884(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43104937

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357884
dbSNP (classic)	rs80357884
ClinGen	rs80357884
ebi	rs80357884
HLI	rs80357884
Exac	rs80357884
Gnomad	rs80357884
Varsome	rs80357884
LitVar	rs80357884
Map	rs80357884
PheGenI	rs80357884
Biobank	rs80357884
1000 genomes	rs80357884
hgdp	rs80357884
ensembl	rs80357884
geneview	rs80357884
scholar	rs80357884
google	rs80357884
pharmgkb	rs80357884
gwascentral	rs80357884
openSNP	rs80357884
23andMe	rs80357884
SNPshot	rs80357884
SNPdbe	rs80357884
MSV3d	rs80357884
GWAS Ctlg	rs80357884

Max Magnitude

6

rs80357884, also known as 351delA, c.232_232delA and p.Arg78Aspfs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357884(-;-)
Alt	rs80357884(-;-)
Reference	Rs80357884(A;A)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41256954delT
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000047802.2, RCV000112087.3,