rs80357836

minus

Geno	Mag	Summary
(-;C)	6	BRCA1 variant considered pathogenic for breast cancer
(C;C)	0	common in clinvar

Make rs80357836(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43094459

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357836
dbSNP (classic)	rs80357836
ClinGen	rs80357836
ebi	rs80357836
HLI	rs80357836
Exac	rs80357836
Gnomad	rs80357836
Varsome	rs80357836
LitVar	rs80357836
Map	rs80357836
PheGenI	rs80357836
Biobank	rs80357836
1000 genomes	rs80357836
hgdp	rs80357836
ensembl	rs80357836
geneview	rs80357836
scholar	rs80357836
google	rs80357836
pharmgkb	rs80357836
gwascentral	rs80357836
openSNP	rs80357836
23andMe	rs80357836
SNPshot	rs80357836
SNPdbe	rs80357836
MSV3d	rs80357836
GWAS Ctlg	rs80357836

Max Magnitude

6

rs80357836, also known as 1191delC, c.1072_1072delC and p.Leu358Cysfs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357836(-;-)
Alt	rs80357836(-;-)
Reference	Rs80357836(C;C)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41246476delG
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000047329.2, RCV000111541.4,