rs80357668

minus

Geno	Mag	Summary
(-;C)	6	BRCA1 variant considered pathogenic for breast cancer
(C;C)	0	common in clinvar

Make rs80357668(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43093355

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357668
dbSNP (classic)	rs80357668
ClinGen	rs80357668
ebi	rs80357668
HLI	rs80357668
Exac	rs80357668
Gnomad	rs80357668
Varsome	rs80357668
LitVar	rs80357668
Map	rs80357668
PheGenI	rs80357668
Biobank	rs80357668
1000 genomes	rs80357668
hgdp	rs80357668
ensembl	rs80357668
geneview	rs80357668
scholar	rs80357668
google	rs80357668
pharmgkb	rs80357668
gwascentral	rs80357668
openSNP	rs80357668
23andMe	rs80357668
SNPshot	rs80357668
SNPdbe	rs80357668
MSV3d	rs80357668
GWAS Ctlg	rs80357668

Max Magnitude

6

rs80357668, also known as 2295delC, c.2176_2176delC and p.Leu726Phefs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357668(-;-)
Alt	rs80357668(-;-)
Reference	Rs80357668(C;C)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41245372delG
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000047744.2, RCV000077508.4,