rs80357535

minus

Geno	Mag	Summary
(-;G)	6	BRCA1 variant considered pathogenic for breast cancer
(G;G)	0	common in clinvar

Make rs80357535(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43094276

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357535
dbSNP (classic)	rs80357535
ClinGen	rs80357535
ebi	rs80357535
HLI	rs80357535
Exac	rs80357535
Gnomad	rs80357535
Varsome	rs80357535
LitVar	rs80357535
Map	rs80357535
PheGenI	rs80357535
Biobank	rs80357535
1000 genomes	rs80357535
hgdp	rs80357535
ensembl	rs80357535
geneview	rs80357535
scholar	rs80357535
google	rs80357535
pharmgkb	rs80357535
gwascentral	rs80357535
openSNP	rs80357535
23andMe	rs80357535
SNPshot	rs80357535
SNPdbe	rs80357535
MSV3d	rs80357535
GWAS Ctlg	rs80357535

Max Magnitude

6

rs80357535, also known as 1374delG, c.1255_1255delG and p.Val419Terfs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357535(-;-)
Alt	rs80357535(-;-)
Reference	Rs80357535(G;G)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41246293delC
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000047395.2, RCV000111574.4,