|?|| (A;A) (A;C) (C;C) ||28|
A study of 1,000 glioblastoma
multiforme cases and 2,000 controls in the US concluded that the PRKDC
(C;C) genotype was associated with an increase in risk for glioblastoma multiforme (odds ratio 1.44, CI: 1.13-1.84).[PMID 19318434
[PMID 19815090] The Relation between Endothelial Nitric Oxide Synthase Gene Variants and Primary Open-Angle Glaucoma: Interactions with Gender and Postmenopausal Hormone Use
[PMID 20590474] Polymorphic Variants of DNA Repair Gene XRCC3 and XRCC7 and Risk of Prostate Cancer: A Study from North Indian Population
[PMID 22634101] Genetic variation in DNA repair gene XRCC7 (G6721T) and susceptibility to breast cancer
[PMID 16400611] Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample.
[PMID 23437280] Comprehensive SNP scan of DNA repair and DNA damage response genes reveal multiple susceptibility Loci conferring risk to tobacco associated leukoplakia and oral cancer
[PMID 23108991] Current evidence on the relationship between three polymorphisms in the XRCC7 gene and cancer risk.
[PMID 26974709] Polymorphisms in double strand break repair related genes influence radiosensitivity phenotype in lymphocytes from healthy individuals.