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rs6707530

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 1.1 in colorectal cancer, may allow cancer cells to invade deeper layers
Make rs6707530(G;T)
Make rs6707530(T;T)
ReferenceGRCh38 38.1/141
Chromosome2
Position215375861
GeneFN1
is asnp
is mentioned by
dbSNPrs6707530
dbSNP (old)rs6707530
ClinGenrs6707530
ebirs6707530
HLIrs6707530
Exacrs6707530
Gnomadrs6707530
Varsomers6707530
Maprs6707530
PheGenIrs6707530
Biobankrs6707530
1000 genomesrs6707530
hgdprs6707530
ensemblrs6707530
gopubmedrs6707530
geneviewrs6707530
scholarrs6707530
googlers6707530
pharmgkbrs6707530
gwascentralrs6707530
openSNPrs6707530
23andMers6707530
23andMe allrs6707530
SNP Nexus

SNPshotrs6707530
SNPdbers6707530
MSV3drs6707530
GWAS Ctlgrs6707530
Max Magnitude1.1
? (G;G) (G;T) (T;T) 28
[PMID 24919860] A single nucleotide polymorphism in fibronectin 1 determines tumor shape in colorectal cancer. (2014 article) "SNP analysis indicated that 44 tumors with a GG genotype at SNP rs6707530 showed significantly higher FN1 expression than did 23 tumors with GT/TT genotypes (p<0.05). The product of the FN1 gene (located at 2q34) is involved in cell adhesion, migration and metastasis in mesenchymal tumors. Abundant expression of FN1 may allow cancer cells to invade deeper layers, which would eventually define tumor shape." (Abstract)